Assays for Virology Research
Measure viral titers by automatic detection and quantification of formed viral plaques and foci using horse radish peroxidase or fluorescent labeling.
Use Celigo to perform high-throughput plaque and foci counting. Load a stack of plates and allow the instrument to image the whole plate and report the number of plaques or foci per well.
Monitor viral infections by direct staining and detection of viral particles within infected cells.
Perform quantification for viral antibody neutralization assays by directly detecting viral particles before and after the addition of antibodies or sera.
Measure transduction efficiencies by imaging and quantifying the fluorescent signal from positively transduced cell lines.
Cytopathic Effect
Measure viral CPE by performing a confluence measurement.
Measure the killing of virally infected cells or cells expressing viral proteins by chimeric antigen receptor (CAR) T-cells.
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